Reaction of Human CO Hemoglobin with p,p'-Difluoro-m,m'-dinitrodiphenylsulfone

Reaction of CO2 with human hemoglobin solution.

The Reaction of n-Butyl Isocyanide with Human Hemoglobin

At pH 7.0, ZOO, both in the absence and presence of phosphates, the time course of n-butyl isocyanide binding to deoxyhemoglobin is biphasic, and the two kinetic phases can be isolated spectrally and identified with the properties of the a and /3 chains. Under all conditions at this pH, both the association and dissociation rate constants of the p chains are at least 10 times larger than the co...

The Reaction of Hemoglobin with Nitrite

Although nitrite has been extensively used as an agent for the formation of methemoglobin, the quantitative relations of the reaction appear to be uncertain; three widely different values have been reported for the amount of methemoglobin formed to nitrite utilized. The first statement of a quantitative relationship was made by Barcroft and Miiller (1) in 1911. In a preliminary report containin...

Hemoglobin Is a Co-Factor of Human Trypanosome Lytic Factor

Trypanosome lytic factor (TLF) is a high-density lipoprotein (HDL) subclass providing innate protection to humans against infection by the protozoan parasite Trypanosoma brucei brucei. Two primate-specific plasma proteins, haptoglobin-related protein (Hpr) and apolipoprotein L-1 (ApoL-1), have been proposed to kill T. b. brucei both singularly or when co-assembled into the same HDL. To better u...

The formaldehyde-hemoglobin reaction.

It is now generally accepted that formaldehyde reacts initially with amino groups of proteins to form methylolamines, which then react more slowly to form methylene bridges between the amino groups and such other groups as the amide group and the phenol& indole, and imidazole rings (Fraenkel-Conrat and Olcott (1) ; Alexander et al. (2)). Some of these bridges are intermolecular. The present pot...